CEREBRAL ATROPHY - Avhandlingar.se

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Brainlesion: Glioma, Multiple Sclerosis, Stroke and Traumatic

Hypertension, APOE ɛ4, types of white matter hyperintensities, and cognitive decline in  Vascular risk factors and severity of white matter hyperintensities: a population-based study, C Qiu et al, 2014. How do elderly persons living at home perceive  White Matter Hyperintensities are No Major Confounder for Alzheimer's Disease Cerebrospinal Fluid Biomarkers. Referentgranskad. Öppen tillgång. Key words: prediabetes, type 2 diabetes, cognitive domains, cognitive decline, dementia, neuroimaging, white matter hyperintensities, cohort  Transient lesions in the white matter (leukoencephalopathy) due to chemotherapy are well-documented in ALL survivors (Bhojwani et al., 2014; Reddick, Glass,  When Weak Becomes Strong: Robust Quantification of White Matter Hyperintensities on Brain MRIs . (Masters Thesis). Delft University of Technology.

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Habes M, Erus G, Toledo JB, Zhang T, Bryan N, Launer LJ, Rosseel Y, Janowitz D, Doshi J, Van der Auwera S, von Sarnowski B, Hegenscheid K, Hosten N, Homuth G, Völzke H, Schminke U, Hoffmann W, Grabe HJ, Davatzikos C Brain 2016 Apr;139 (Pt 4):1164-79. Background: White matter hyperintensities, prevalent in patients with Parkinson's disease (PD), significantly affect parkinsonian motor symptoms. The objective of this study was to investigate the relationship between white matter hyperintensities and nigrostriatal dopamine depletion and their interaction or mediating effects on motor symptoms in patients with drug-naive early-stage PD. Se hela listan på ahajournals.org White Matter Hyperintensities White matter hyperintensities (WMHs) are the bright spots on T2-weighted brain MRI scans. They are very common in elderly individuals, they are more prevalent in people with high blood pressure and other vascular risk factors, and they are associated with poorer cognition.

White matter hyperintensities as a predictor of neuropsychological

4  According to Charles DeCarli, the director of UC Davis Alzheimer's Disease Center, these areas may indicate some type of injury to the brain, perhaps due to decreased blood flow in that area. White matter hyperintensities can be caused by a variety of factors including ischemia, micro- hemorrhages, gliosis, damage to small blood vessel walls, breaches of the barrier between the cerebrospinal fluid and the brain, or loss and deformation of the myelin sheath. The effect of white matter hyperintensities on UPDRS total score and bradykinesia subscore was indirectly mediated by dopamine transporter availability in the posterior putamen, whereas the axial sub-score was directly affected by white matter hyperintensities. White matter hyperintensities (WMHs) are clinically silent abnormalities visible in deep or periventricular white matter on CT or MRI. They are particularly apparent on FLAIR MRI, which is a T2-weighted sequence where the CSF signal is suppressed.

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2021-03-25 · White matter hyperintensity volume, type and shape correlated with an increased risk for mortality and ischemic stroke among patients with manifest arterial disease, according to findings from the 2013-05-09 · Background White matter hyperintensities (WMH) lesions on T2/FLAIR brain MRI are frequently seen in healthy elderly people. Whether these radiological lesions correspond to irreversible histological changes is still a matter of debate. We report the radiologic-histopathologic concordance between T2/FLAIR WMHs and neuropathologically confirmed demyelination in the periventricular, perivascular 2020-10-08 · White matter hyperintensities (WMH) are very frequent in older adults and associated with worse cognitive performance. Little is known about the links between WMH and vascular risk factors, cortical β-amyloid (Aβ) load, and cognition in cognitively unimpaired adults across the entire lifespan, especially in young and middle-aged adults. 2018-07-02 · Background White matter hyperintensities (WMHs) are frequently detected in migraine patients. However, their significance and correlation to migraine disease burden remain unclear. This study aims to examine the correlation of WMHs with migraine features and explore the relationship between WMHs and migraine prognosis.

White matter hyperintensities

N2 - Patients with migraine are at increased risk for white matter hyperintensities detected on magnetic resonance imaging. The presence of nonspecific white matter hyperintensities may cause uncertainty for physicians and anxiety for patients. The pathophysiology and long-term consequences of these lesions are unknown.
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Our findings add to a growing body of literature suggesting WMH is a marker for frailty. © The Author (s) 2020. Published by Oxford University Press on behalf of The Gerontological Society of America.

White matter hyperintensities (WMH) is a non-specific term that refers to white matter (WM) signal hyperintensity areas on T2 weighted MRI scans, and correlates with WM rarefaction (leucoaraiosis) as defined on CT scans. 1 The main risk factors associated with development of WMH are older age and blood hypertension. 2 WMH occur both in demented patients and in healthy elderly subjects, and their relevance to cognitive status has not been fully established.
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(Masters Thesis). Delft University of Technology. Retrieved  BrainLes 2017, as well as the International Multimodal Brain Tumor Segmentation, BraTS, and White Matter Hyperintensities, WMH, segmentation challenges,  När det förekommer i de basala ganglierna delen av hjärnan, detta kallas subkortikala hyperintensities.


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Vad Är White Matter Hyperintensitet? / Threebackyards.com

1 The main risk factors associated with development of WMH are older age and blood hypertension. 2 WMH occur both in demented patients and in healthy elderly subjects, and 2020-01-20 · CONCLUSION: We provide evidence for an association between baseline white matter hyperintensities and progression of frailty. Our findings add to a growing body of literature suggesting WMH is a marker for frailty.